Recent research at the University of São Paulo in Brazil has demonstrated that high-frequency ultrasound waves can effectively destroy SARS-CoV-2,

 

Recent research from scientists at the University of São Paulo in Brazil has demonstrated that high-frequency ultrasound waves can effectively destroy SARS-CoV-2, the virus causing COVID-19, and influenza A (H1N1) viruses in laboratory settings.

Using frequencies between 3 and 20 MHz—similar to those employed in routine medical imaging—the team exposed viral particles suspended in solution to these sound waves.

The mechanism relies on acoustic resonance. Viral envelopes, composed of lipid membranes and spike proteins, have physical dimensions and mechanical properties that match the ultrasound frequencies. When hit by the waves, the viruses absorb the acoustic energy, causing them to vibrate intensely.

This leads to structural instability, membrane rupture, fragmentation, and eventual explosion in a process likened to a "popcorn effect." Electron microscopy revealed severe morphological damage, rendering the viruses non-infectious.

Importantly, the same ultrasound intensities did not harm human cells, as mammalian cells lack the precise resonant frequencies of the smaller viral particles.

This selectivity highlights a physical rather than chemical approach, avoiding traditional drug resistance issues.

Experiments confirmed reduced viral loads in cell cultures post-treatment, opening avenues for potential applications in air purification, surface disinfection, or even therapeutic devices.

While still in early lab stages, the findings suggest ultrasound could complement existing antiviral strategies against enveloped viruses like dengue or Zika